Often when developing new radio-pharmaceuticals or medical devices, there are no available radiation transport physics models available that are applicable for proper determination of dosimetry. For example, for a recently FDA approved radiation containing medical device, a radiation filled "balloon" is implanted into a brain tumor resection cavity. The development of this device required that dosimetry estimates for resection margins as a function of depth be produced for a number of isotopes.
Applicable physics models for this determination did not exist in the published literature. CDE developed these models, and did dosimetry determinations for the implantation, and the dosimetry analysis for the potential balloon failure scenario.
CDE can produce physics models using the highly validated MCNP Monte Carlo Transport Code. Such models can be created for almost any scenario including:
  • Abnormal and Normal Organs.
  • Tumors.
  • Brachytherapy Devices.
  • Intravascular Brachytherapy
  • Medical and Occupational Worker Exposures From a Variety of Sources.
  • Exposure to Others From Patients.
  • Organ Substructures.
  • Extravasation Therapy
CDE staff has created numerous radiation transport physics models including brain resection cavities, patient to family member, vaginal activity, brain ventricles model, unshielded Tc-99m generator source in human hand model, blood vessel suture, tumor encasing nerve, tumor adjacent to pericardium, and many others.
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